Harman hydrochloride

CAS No. 21655-84-5

Harman hydrochloride ( Harmane hydrochloride(486-84-0 Free base) )

Catalog No. M27979 CAS No. 21655-84-5

Harman hydrochloride can directly induce CYP1A1 gene expression in an AhR-dependent manner and may represent a novel mechanism by which harman promotes mutagenicity, co-mutagenicity and carcinogenicity.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 35 Get Quote
5MG 54 Get Quote
10MG 77 Get Quote
25MG 138 Get Quote
50MG 210 Get Quote
100MG 314 Get Quote
200MG 471 Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    Harman hydrochloride
  • Note
    Research use only, not for human use.
  • Brief Description
    Harman hydrochloride can directly induce CYP1A1 gene expression in an AhR-dependent manner and may represent a novel mechanism by which harman promotes mutagenicity, co-mutagenicity and carcinogenicity.
  • Description
    Harman hydrochloride can directly induce CYP1A1 gene expression in an AhR-dependent manner and may represent a novel mechanism by which harman promotes mutagenicity, co-mutagenicity and carcinogenicity.
  • Synonyms
    Harmane hydrochloride(486-84-0 Free base)
  • Pathway
    Metabolic Enzyme/Protease
  • Target
    P450
  • Recptor
    Autophagy
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    21655-84-5
  • Formula Weight
    218.7
  • Molecular Formula
    C12H11ClN2
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    Cc1nccc2c1[nH]c1c2cccc1.Cl
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Páchniková G, et al. Substituted 2-hydroxy-N-(arylalkyl)benzamide sensitizes cancer cells to metabolic stress by disrupting actin cytoskeleton and inhibiting autophagic flux. Toxicol In Vitro. 2016 Dec;37:70-78.
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